Abstract

Personalized and Patient-Centered Approach to Patients with Included Upper Canines

by Barbato Ersilia

The impaction of maxillary canines presents a clinical challenge that modern orthodontics is addressing with a model increasingly oriented toward "precision" and "personalization." Implementing early interceptive therapy is considered the "gold standard" to prevent complications, but this requires accurate and timely diagnosis. In this regard, the advancements in molecular medicine and genomics, integrated with artificial intelligence, are crucial as they offer a deep understanding of the biological and molecular bases of dental anomalies. Research has shown that comprehending the genetic basis of odontogenesis, with particular attention to the role of miRNAs, is vital for personalized diagnosis and prognosis. This approach opens up future scenarios where genetics will become an integral part of clinical practice, allowing for the identification of the underlying mechanisms that influence the eruption of maxillary canines. The result is a diagnostic and therapeutic approach that goes beyond the biomechanical aspects to ensure a more effective, targeted, and truly patient-centered treatment.

Learning Objectives

After this lecture, you will be able to identify dento-skeletal anomalies associated with the risk of maxillary canine impaction, with the aim of ensuring early clinical interception.
After this lecture, you will be able to define the diagnostic approaches and the impact of genetics and molecular biology on the issue of maxillary canine impaction.
After this lecture, you will be able to evaluate future diagnostic, prognostic, and therapeutic perspectives in light of the advancements in translational and interdisciplinary research.